With PARTdesigner you can cut a cavity (e.g. hole, etc.) out of a 3D body (e.g. cuboid, cylinder, etc.).

Draw a 2D contour in the Sketcher and extrude or rotate it using the context menu command Section [Cut] -> Extrude... /Rotate.... [Rotate...] The figure described in this way is spatially subtracted from the 3D solid.

Example with extruded sketch of a rectangle (Base) and rotated cut circle (Cut)

The approach of extrusion and rotation is principally according to the explained under Section 7.6.2.6, “ Base extrude / Base rotate ”.